Lectures & Slides

The following slides are kindly made available by their authors

Lectures not listed here but in the programme are not available for download.
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Group Sequential and Adaptive Design for Confirmatory Trials using East

Regulatory Topics and Guidelines
  • EMA Guidance Documents: Overview of Recent Developments (T. Lang)
  • The Changing Environment for Drug Development and Drug Licensing in Europe after ICH (J. Röhmel)
Multiple Comparisons
  • Statistical Criteria for Components of Primary Composite Endpoint to Support Benefit-Risk Assessment at an Interim Analysis Using Blinded Data (J. Brumm)
  • A Parametric Rüger Test and Diagnostic Trials (R. Ristl, C. Gartner, T. Lang, M. Posch)
Recent Advances in Time-to-Event Models
  • Practical Implications of Competing Risk Models – How to Interpret the Results to Clinicians (M. Smastuen)
  • Understanding Treatment Mechanisms in Clinical Survival Trials – A Causal Approach (S. Strohmaier, T. Pedersen, T. Lange, Ø. Borgan, O.O. Aalen)
Health Technology Assessment (HTA)
  • Biometrical Issues in Health Technology Assessment (R. Bender)
  • Designing Drug Development to Optimize HTA Submissions (K. Facey)
  • Statistics in Health Technology Assessment: Issues and Challenges (Y. Castro)
Multiregional Trials
  • Multiregional Clinical Trials: Introduction to Basic Features and Discussion of Special Issues (B. Jones, P. Gallo)
  • Heterogeneity in Multiregional Studies (J. Röhmel)
Multistate Models – Cure Models
  • Cure Models Based on Univariate and Bivariate Random Effects (A. Wienke)
  • A New Approach Based on Pseudo-Values for Assessing the Effect of a Binary Time-Dependent Covariate on Patient Survival (U. Pötschger, H. Heinzl, A. Attarbaschi, M. Minkov, M. Mittlböck)
  • Multistate Models with Multiple Time Scales (B. Carstensen, S. Iacobelli)
Flexible and Adaptive Designs
  • Treatment Selection in Multi-Arm, Multi-Stage Clinical Trials (T. Jaki, D. Magirr, N. Stallard)
  • Case Studies for Adaptive Treatment Arm Selection and Population Enrichment Designs (G. Wassmer)
  • Type I Error Rate Control in Adaptive Clinical Trials with blinded interim Analysis (M. Posch, M. Malina)
  • Population Enrichment Designs for Molecularly Targeted Therapies in Oncology (C. Mehta)
Analysis of Registries and Large Databases
  • Analysis of Large Registry-Based Study of Prescription Drugs and Road Traffic Crashes (M. Avalos, L. Orriols)
  • Mammography Screening and Cancer Registration in Tyrol/Austria (W. Oberaigner)
  • Observational Studies, Matching and Propensity Scores: An Application to Colorectal Cancer Data (J. Hinde, C. Dooley)
  • The Use of Propensity Scores in Observational Trials (J. Alsop)
Growth Curves: GAMLSS, SITAR and Austrian Kids
  • Development of New Austrian Height and Weight References (A. Gleiss, G. Häusler, M. Schemper)
  • SITAR Growth Curve Analysis to Evaluate Interventions and Life Course Outcomes (T. Cole)
Statistics in Drug Development
  • Developing Drugs for Reimbursement – Current and Future Challenges for Statisticians (M. Scott)
Risk Prediction
  • Shrinkage of Regression Coefficients: Old Concepts and New Ideas (D. Dunkler, G. Heinze)
  • On Criteria for Evaluating Risk Prediction Models for Public Health Applications (R. Pfeiffer)
  • Changes of Body Mass Index in Relation to Mortality: Results of a Cohort of 42,099 Adults (G. Nagel, K. Rapp, H. Ulmer, H. Concin, J. Klenk)
  • Evaluating Disease Predictors with Repeated Measurements: A Longitudinal Study of Alzheimer's Disease (L. Brant)
  • Some Applications of Risk Modeling in Breast Cancer Prevention (M. Gail)
Mixed Data Analysis
  • Joint Analysis of Mixed Outcome Data: Issues and Challenges (K. Chough)
  • Hierarchical Modeling of Endpoints of Different Types with Generalized Linear Mixed Models (C. Faes)
  • Updating the Probability of Success of Clinical Development Programs Over Time (M. Abt, P. Jordan)
Young Statisticians
  • Efficient Data-Augmented MCMC Methods for Binomial Logit Models (A. Fussl, S. Frühwirth-Schnatter, R. Frühwirth)
  • Problems of INLA in Generalized Linear Mixed Models for Binary Responses (R. Sauter, L. Held)
  • Analysis of Association on Non-Product Spaces (A. Klimova)
  • Statistical Methods for Improvement of Motif Finding Algorithms (Ž Stepančič)
  • Overrunning Data Methods: Comparisons Based on Real Data Trials (N. Soriani, I. Baldi, D. Gregori)
Statistical Methods in Genetic Epidemiology
  • Max-test to Evaluate Genetic Association Studies for Continuous and Time-to-Event Traits (L. Hothorn, E. Herberich)
  • Using Weighted Genetic Predisposition Scores to Evaluate Gene-Environment Interaction Effects on Lipid Levels (C. Lamina, L. Forer, S. Schönherr, B. Kollerits, J. Ried, C. Gieger, A. Peters, H.E. Wichmann, F. Kronenberg)
  • Using the LASSO and Ridge Regression in Case-Control Studies with Zero-Inflated Predictors (M. Kohl, G. Heinze)
Statistical Methods in Infectious Disease Epidemiology
  • Estimating MMR Vaccine Coverage from Australian Sero-Surveillance Data (N. Hens, J. Wood, N. Goeyvaerts)
  • Recent Development in Identifying Transmission Routes of Healthcare Associated Infections using Whole Genome Sequence Data (T. Kypraios)
  • Sample Size Calculations and the Temporal Dependency between an Infection and its Sequela in Randomised Controlled Trials (S. Herzog, A. Berghold)
  • Modelling Power-Law Spread in Infectious Diseases (S. Meyer, L. Held)
Statistical Evaluation of Biomarkers and Clinical Tools
  • Development in Prostate Cancer Risk Predition Tools in Response to Changes in Clinical Landscape (D. Ankerst)
  • Comparison and Evaluation of Cardiac Biomarkers in Patients with Intermittent Claudication: Results from the CAVASIC Study (B. Kollerits, G. Sturm, C. Lamina, A. Hammerer-Lercher, B. Rantner, M. Stadler, T. Ziera, J. Struck, P. Klein-Weigel, G. Fraedrich, F. Kronenberg)
  • Stopping Rules for Sequential Trials in High-Dimensional Data (S. Zehetmayer, M. Posch, A. Graf)
Biometrics – From Bench to Trials
  • A Novel Method to Estimate the Minimum Effective Dose for Monotone and Non-Monotone Dose-Response Relationships (M.J. Wolfsegger, G. Gutjahr, W. Engl, T. Jaki)
  • Nonparametric Multivariate Density Estimation Using Mixtures (X. Wang, Y. Wang)
  • How Often are you Hit by an Infection? – A Likelihood Approach to Determine the Multiplicity of Infection (K. Schneider)
Please download all available slides here:   PDF 
Opens in a new window.

Lectures not listed here but in the programme are not available for download.
If your presentation should or should not be listed there, please contact us.